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Gen9 joins synthetic genome project to build Yeast 2.0

Gen9, Inc., a developer of scalable technologies for synthesizing genes, has been selected to take part in the Synthetic Yeast Project Sc2.0, organized and hosted by Johns Hopkins University (JHU) School of Medicine. (Earlier post.) Gen9 will use its proprietary next-generation gene synthesis technology to contribute to the project.

The Synthetic Yeast Project aims to use yeast, S. cerevisiae, as the basis for a new engineered synthetic life form, Sc2.0, that can be used to answer a wide variety of questions about fundamental properties of chromosomes, genome organization, gene content, the function of RNA splicing, and questions relating to genome structure and evolution. Members of the project will design, build, and assemble synthetic yeast chromosomes.

As a participant in the project, Gen9 will synthesize DNA corresponding to chromosome 9 of the yeast genome, a region encompassing about 90Kb. JHU Professor Jef Boeke, founder of the Synthetic Yeast Project, will advise Gen9 on the work.

Gen9 is a privately held gene synthesis and synthetic biology company with a rapidly growing portfolio of products. Currently, Gen9 is manufacturing and shipping double-stranded GeneBits DNA constructs (up to 1000 base pairs in length), and GeneBytes DNA constructs (from 1000 base pairs to 3000 base pairs). Also, by the end of 2013, Gen9 will begin selling synthesized DNA constructs as long as 10Kb. All of Gen9’s products are sequence verified and sent as clonal, either in a vector or as linear DNA.


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