ACGT and Synthetic Genomics Complete First Draft of Oil Palm Genome; Jatropha Sequencing Progressing
21 May 2008
The Asiatic Centre for Genome Technology Sdn Bhd (ACGT) and Synthetic Genomics Inc. (SGI) have completed a first draft assembly and annotation of the oil palm genome. (Earlier post.) The organizations also announced that they have made progress in sequencing and analyzing the jatropha genome.
The oil palm and jatropha genome projects represent the first stages of research undertaken through a joint venture between SGI and ACGT which was announced in 2007 and is aimed at developing more high-yielding and disease-resistant plant feedstocks.
The genome sequences of these highly productive oilseed crops will enable the in-depth understanding of genes encoding for plant yield and health and foster the development of improved plant varieties. We are also characterizing the important microbes living in the environments around these plants. Our goal is to harness this knowledge to produce improved feedstocks, renewable fuels, biofertilizers, and disease-control solutions.
—J. Craig Venter, Ph.D., founder and CEO of Synthetic Genomics
The oil palm genome is approximately 1.8 billion base pairs in size, about four times the size of the rice genome and two thirds the size of the maize genome. The groups sequenced a combination of two oil palm races—tenera and dura—to produce seven-fold coverage of the plant’s genome, which represents the most comprehensive sequence and analysis of this genome. SGI and ACGT will continue to do additional sequencing and analysis of the oil palm genome and when completed, this will become the reference genome.
The two are also conducting an in-depth genomic, physiological and biochemical analysis of jatropha. Since jatropha is a non-domesticated crop with few published studies, it has significant potential for improvements in yield and agronomic properties, according to the partners. The jatropha genome is 500 million base pairs in size, similar to the size of the rice genome. The organizations will continue to sequence and analyze the jatropha genome to achieve ten-fold coverage.
The draft oil palm genome is already yielding important information including unique genetic variations linked to traits that differ in the two races. One example of this pertains to kernel shell thickness which differs between the two. Since fruits with thinner kernel shells yield more oil, the groups are seeking to understand the genetic basis for shell thickness. These molecular markers and others can be used in breeding and tissue-culture based approaches to address plant yield, oil quality, growth and height and other important properties, including fertilizer requirements and stress and disease tolerance.
ACGT is a wholly owned subsidiary of Asiatic Development Berhad, an oil palm plantation company listed on Bursa Malaysia (Malaysian Stock Exchange) and a member of the Genting Group. Asiatic Development Berhad, a 55%-owned subsidiary of Genting Berhad, commenced its operations in 1980 as the plantation arm of the Genting Group.
The Asiatic Group has 66,000 hectares of land in Malaysia and is developing 98,300 hectares in Indonesia on a joint venture basis. The Group owns 5 oil mills with a total milling capacity of 235 tonnes per hour and is reputed to be one of the lowest cost palm oil producers with fresh fruit bunches production of over one million tonnes. Asiatic is one of the early members of the Roundtable on Sustainable Palm Oil (RSPO).
Synthetic Genomics Inc. is focusing on genomic-driven solutions to address global energy and environmental challenges. The company’s main research and business programs are focused on major bioenergy areas: designing advanced biofuels with superior properties compared to ethanol and biodiesel; harnessing photosynthetic organisms to produce value added products directly from sunlight and carbon dioxide; developing new biological solutions to increase production and/or recovery rates of subsurface hydrocarbons and developing high-yielding, more disease resistant and economic feedstocks.
Just don't make them resistant to EVERYTHING. We don't need another Kudzu.
Posted by: NCyder | 21 May 2008 at 06:51 AM
Do not disease resistant organisms select disease mutations? Are there long term studies on the effect of GMO disease/pest resistance?
Posted by: sulleny | 21 May 2008 at 07:52 AM
Making oil palms resistant to dry conditions or cold weather would be a neat trick.
Posted by: Reality Czech | 21 May 2008 at 08:17 AM
Can't someone find a use for Kudzu?
Posted by: DS | 21 May 2008 at 10:37 AM
Nitrogen fixing oil palms in the desert that require only the water and CO2 in the air to thrive and produce. That would be a nice gene engineering trick.
Posted by: Al Fin | 22 May 2008 at 10:29 AM