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DOE Awards Novozymes $12.3M to Increase Efficiency of Enzymes for Cellulosic Ethanol Production 2x

Novozymes is seeking to decrease the dosage of enzymes required for the hydrolysis stage of cellulosic ethanol production. Click to enlarge. Credit: Novozymes

The US Department of Energy (DOE) awarded Novozymes a $12.3 million contract to improve the enzymes necessary to produce cellulosic ethanol. Novozymes’ project DECREASE (Development of a Commercial-Ready Enzyme Application System for Ethanol) aims to improve the performance of Novozymes’ most advanced enzyme system by decreasing the dosage of enzyme required to hydrolyze biomass into fermentable sugars suitable for cellulosic ethanol production. (Earlier post.)

Under the terms of the 2.5-year contract, Novozymes has committed to increase the efficiency of the enzymes used in the conversion of cellulosic biomass to ethanol by two-fold. In combination with internally funded research and development to reduce enzyme production costs, this work will enable Novozymes to supply new and even more cost-efficient commercial cellulases in pilot, demonstration, and commercial plants by 2012. Novozymes will match the DOE funding, bringing the total investment of the research project to $25 million.

Development of commercially viable enzymes for the production of cellulosic ethanol is the largest research and development effort in Novozymes’ history with more than 100 employees allocated. Novozymes has already confirmed plans to launch the enzymes required for commercially viable production of ethanol from cellulose by 2010, midway through this contract, and now plans to reach an enzyme cost target that is even further reduced by 2012. This target is based on the use of corn stover as biomass feedstock.

This is the second contract Novozymes has received from the DOE. The first was awarded in 2001 for $18 million, targeting both improved enzymes and production processes for biofuel production. This latest contract will build on those results, specifically targeting the identification and implementation of more efficient enzymes.

In addition to the contract work, Novozymes is working to optimize the efficiency of enzymes on other pretreatments and second-generation feedstocks such as straws, sugarcane bagasse, and wood. The company is currently supplying experimental enzymes to a wide range of development partners in the US, China, Brazil, and Europe. Novozymes is currently the world’s largest supplier of enzymes for the existing first-generation (corn) ethanol industry.

DONG Energy in Denmark earlier this year pre-qualified Novozymes as supplier of enzymes for its new second-generation bioethanol demonstration factory, which will use straw as a feedstock. DONG began construction on the plant in Kalundborg in August; production is targeted for November 2009—the time of the Climate Change Conference in Copenhagen.

Project DECREASE is carried out as a global collaboration between Novozymes researchers in California, Denmark, and China and our external partners: the Pacific Northwest National Laboratory, the National Renewable Energy Laboratory, and Cornell University in the US, and Centre National de la Recherche Scientifique in France.



More positive news for the second gen cellulosic industry. Hopefully they will be looking at a wide variety of feedstocks including switchgrass, cereal straw and stover.

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