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DEINOVE produces muconic acid from cellulosic substrates

DEINOVE, a biotech company developing innovative processes for producing biofuels and bio-based chemicals by using Deinococcus bacteria, has produced muconic acid in their laboratory using second-generation substrates. (Earlier post.)

DEINOVE recently announced that it had deployed a new R&D platform dedicated to the production of muconic acid, a versatile chemical intermediate the derivatives of which—caprolactam, terephthalic acid (a precursor to PET) and adipic acid—are widely used in the plastics industry (notably for automotive and packaging applications), the production of synthetic fibers for textiles or industry (mainly nylon) and food (acidifying agent).

DEINOVE has since obtained proof of concept in their laboratory for the transformation of second-generation cellulose-based materials into muconic acid. Furthermore, the improvements made to the strains have made it possible to multiply production by five compared to the previous trials carried out on monosaccharide-based model substrates, glucose and xylose.

Cellulose is one of the main components in biomass, plants and wood, as well as in paper and cardboard (also called second-generation materials). This is a complex molecule (sugar chains with 6 carbon atoms) that have to be broken down into monosaccharides before fermentation (hydrolysis).

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